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Structurally-defined αMHC-II nanobody-drug conjugates: Therapeutic and imaging platforms for B-cell lymphoma
Antibody-drug conjugates (ADCs) of defined structure hold great promise for cancer therapies, but further advances are constrained by the complex structures of full-sized antibodies. Camelid-derived single domain antibody fragments (VHHs or nanobodies) offer possible solutions to this challenge by p...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820396/ https://ncbi.nlm.nih.gov/pubmed/26840214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201509432 |
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