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HypE-specific Nanobodies as Tools to Modulate HypE-mediated Target AMPylation
The covalent addition of mono-AMP to target proteins (AMPylation) by Fic domain-containing proteins is a poorly understood, yet highly conserved post-translational modification. Here, we describe the generation, evaluation, and application of four HypE-specific nanobodies: three that inhibit HypE-me...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4424278/ https://ncbi.nlm.nih.gov/pubmed/25678711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634287 |
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