Cell-autonomous and cell non-autonomous downregulation of tumor suppressor DAB2IP by microRNA-149-3p promotes aggressiveness of cancer cells

The tumor suppressor DAB2IP contributes to modulate the network of information established between cancer cells and tumor microenvironment. Epigenetic and post-transcriptional inactivation of this protein is commonly observed in multiple human malignancies, and can potentially favor progression of t...

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Veröffentlicht in:Cell Death Differ
Hauptverfasser: Bellazzo, Arianna, Di Minin, Giulio, Valentino, Elena, Sicari, Daria, Torre, Denis, Marchionni, Luigi, Serpi, Federica, Stadler, Michael B., Taverna, Daniela, Zuccolotto, Gaia, Montagner, Isabella Monia, Rosato, Antonio, Tonon, Federica, Zennaro, Cristina, Agostinis, Chiara, Bulla, Roberta, Mano, Miguel, Del Sal, Giannino, Collavin, Licio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030048/
https://ncbi.nlm.nih.gov/pubmed/29568059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0088-5
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