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αO-Conotoxin GeXIVA Disulfide Bond Isomers Exhibit Differential Sensitivity for Various Nicotinic Acetylcholine Receptors but Retain Potency and Selectivity for the Human α9α10 Subtype

Nicotinic acetylcholine receptor (nAChR) subtypes exhibit distinct neuropharmacological properties that are involved in a range of neuropathological conditions, including pain, addiction, epilepsy, autism, schizophrenia, Tourette’s syndrome, Alzheimer’s and Parkinson’s diseases, as well as many type...

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Bibliografiske detaljer
Udgivet i:Neuropharmacology
Main Authors: Zhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Wu, Yong, Craik, David J., McIntosh, J. Michael, Luo, Sulan
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029978/
https://ncbi.nlm.nih.gov/pubmed/28416445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.04.015
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