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Cx43 Overexpression in Osteocytes Prevents Osteocyte Apoptosis and Preserves Cortical Bone Quality in Aging Mice

Young, skeletally mature mice lacking Cx43 in osteocytes exhibit increased osteocyte apoptosis and decreased bone strength, resembling the phenotype of old mice. Further, the expression of Cx43 in bone decreases with age, suggesting a contribution of reduced Cx43 levels to the age‐related changes in...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:JBMR Plus
Main Authors: Davis, Hannah M, Aref, Mohammad W, Aguilar‐Perez, Alexandra, Pacheco‐Costa, Rafael, Allen, Kimberly, Valdez, Sinai, Herrera, Carmen, Atkinson, Emily G, Mohammad, Arwa, Lopez, David, Harris, Marie A, Harris, Stephen E, Allen, Matthew, Bellido, Teresita, Plotkin, Lilian I
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029870/
https://ncbi.nlm.nih.gov/pubmed/29978155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10035
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