Frequent interferon regulatory factor 1 (IRF1) binding at remote elements without histone modification

Transcriptional activators bind DNA and recruit cofactors to modify chromatin. The extent to which these two events are separable is unclear. Here, using a custom ChIP tiling array to map chromatin modifications, we show that interferon-γ-induced DNA binding of signal transducer and activator of tra...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Abou El Hassan, Mohamed, Huang, Katherine, Xu, Zhaodong, Yu, Tao, Bremner, Rod
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028979/
https://ncbi.nlm.nih.gov/pubmed/29748386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002889
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