Properties of STAT1 and IRF1 enhancers and the influence of SNPs

BACKGROUND: STAT1 and IRF1 collaborate to induce interferon-γ (IFNγ) stimulated genes (ISGs), but the extent to which they act alone or together is unclear. The effect of single nucleotide polymorphisms (SNPs) on in vivo binding is also largely unknown. RESULTS: We show that IRF1 binds at proximal o...

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Detalhes bibliográficos
Publicado no:BMC Mol Biol
Main Authors: Abou El Hassan, Mohamed, Huang, Katherine, Eswara, Manoja B. K., Xu, Zhaodong, Yu, Tao, Aubry, Arthur, Ni, Zuyao, Livne-bar, Izzy, Sangwan, Monika, Ahmad, Mohamad, Bremner, Rod
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343312/
https://ncbi.nlm.nih.gov/pubmed/28274199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-017-0084-1
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