Properties of STAT1 and IRF1 enhancers and the influence of SNPs

BACKGROUND: STAT1 and IRF1 collaborate to induce interferon-γ (IFNγ) stimulated genes (ISGs), but the extent to which they act alone or together is unclear. The effect of single nucleotide polymorphisms (SNPs) on in vivo binding is also largely unknown. RESULTS: We show that IRF1 binds at proximal o...

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Publicado en:BMC Mol Biol
Autores principales: Abou El Hassan, Mohamed, Huang, Katherine, Eswara, Manoja B. K., Xu, Zhaodong, Yu, Tao, Aubry, Arthur, Ni, Zuyao, Livne-bar, Izzy, Sangwan, Monika, Ahmad, Mohamad, Bremner, Rod
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343312/
https://ncbi.nlm.nih.gov/pubmed/28274199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-017-0084-1
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