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Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina

In the Chx10-null ocular retardation (or(J)) mouse, retinal progenitor cell (RPC) proliferation is impaired, and bipolar neurons, a late born cell type, fail to differentiate. It is unclear whether Chx10 is required to maintain proliferation throughout retinogenesis or whether the bipolar cell defec...

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Detalhes bibliográficos
Main Authors: Livne-bar, Izzy, Pacal, Marek, Cheung, Melissa C., Hankin, Mark, Trogadis, Judy, Chen, Danian, Dorval, Kimberley M., Bremner, Rod
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458782/
https://ncbi.nlm.nih.gov/pubmed/16547132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600083103
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