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Epigenetic regulatory elements associate with specific histone modifications to prevent silencing of telomeric genes

In eukaryotic cells, transgene expression levels may be limited by an unfavourable chromatin structure at the integration site. Epigenetic regulators are DNA sequences which may protect transgenes from such position effect. We evaluated different epigenetic regulators for their ability to protect tr...

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Detalhes bibliográficos
Main Authors: Majocchi, Stefano, Aritonovska, Elena, Mermod, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874193/
https://ncbi.nlm.nih.gov/pubmed/24071586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt880
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