Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease

α-Galactosidases (EC 3.2.1.22) are retaining glycosidases that cleave terminal α-linked galactose residues from glycoconjugate substrates. α-Galactosidases take part in the turnover of cell wall–associated galactomannans in plants and in the lysosomal degradation of glycosphingolipids in animals. De...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kytidou, Kassiani, Beekwilder, Jules, Artola, Marta, van Meel, Eline, Wilbers, Ruud H. P., Moolenaar, Geri F., Goosen, Nora, Ferraz, Maria J., Katzy, Rebecca, Voskamp, Patrick, Florea, Bogdan I., Hokke, Cornelis H., Overkleeft, Herman S., Schots, Arjen, Bosch, Dirk, Pannu, Navraj, Aerts, Johannes M. F. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028973/
https://ncbi.nlm.nih.gov/pubmed/29674318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001774
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