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UV damage endonuclease employs a novel dual-dinucleotide flipping mechanism to recognize different DNA lesions
Repairing damaged DNA is essential for an organism’s survival. UV damage endonuclease (UVDE) is a DNA-repair enzyme that can recognize and incise different types of damaged DNA. We present the structure of Sulfolobus acidocaldarius UVDE on its own and in a pre-catalytic complex with UV-damaged DNA c...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553973/ https://ncbi.nlm.nih.gov/pubmed/23221644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1127 |
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