Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease

α-Galactosidases (EC 3.2.1.22) are retaining glycosidases that cleave terminal α-linked galactose residues from glycoconjugate substrates. α-Galactosidases take part in the turnover of cell wall–associated galactomannans in plants and in the lysosomal degradation of glycosphingolipids in animals. De...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Kytidou, Kassiani, Beekwilder, Jules, Artola, Marta, van Meel, Eline, Wilbers, Ruud H. P., Moolenaar, Geri F., Goosen, Nora, Ferraz, Maria J., Katzy, Rebecca, Voskamp, Patrick, Florea, Bogdan I., Hokke, Cornelis H., Overkleeft, Herman S., Schots, Arjen, Bosch, Dirk, Pannu, Navraj, Aerts, Johannes M. F. G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Enzymology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028973/
https://ncbi.nlm.nih.gov/pubmed/29674318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001774
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