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Edaravone and cyclosporine A as neuroprotective agents for acute ischemic stroke

It is well known that acute ischemic stroke (AIS) and subsequent reperfusion produce lethal levels of reactive oxygen species (ROS) in neuronal cells, which are generated in mitochondria. Mitochondrial ROS production is a self‐amplifying process, termed “ROS‐induced ROS release”. Furthermore, the mi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acute Med Surg
Hauptverfasser: Matsumoto, Shohei, Murozono, Michihiro, Kanazawa, Masahiro, Nara, Takeshi, Ozawa, Takuro, Watanabe, Yasuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028804/
https://ncbi.nlm.nih.gov/pubmed/29988669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ams2.343
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