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Edaravone and cyclosporine A as neuroprotective agents for acute ischemic stroke

It is well known that acute ischemic stroke (AIS) and subsequent reperfusion produce lethal levels of reactive oxygen species (ROS) in neuronal cells, which are generated in mitochondria. Mitochondrial ROS production is a self‐amplifying process, termed “ROS‐induced ROS release”. Furthermore, the mi...

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Detalhes bibliográficos
Publicado no:Acute Med Surg
Main Authors: Matsumoto, Shohei, Murozono, Michihiro, Kanazawa, Masahiro, Nara, Takeshi, Ozawa, Takuro, Watanabe, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028804/
https://ncbi.nlm.nih.gov/pubmed/29988669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ams2.343
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