Edaravone and cyclosporine A as neuroprotective agents for acute ischemic stroke

It is well known that acute ischemic stroke (AIS) and subsequent reperfusion produce lethal levels of reactive oxygen species (ROS) in neuronal cells, which are generated in mitochondria. Mitochondrial ROS production is a self‐amplifying process, termed “ROS‐induced ROS release”. Furthermore, the mi...

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Bibliografiske detaljer
Udgivet i:Acute Med Surg
Main Authors: Matsumoto, Shohei, Murozono, Michihiro, Kanazawa, Masahiro, Nara, Takeshi, Ozawa, Takuro, Watanabe, Yasuo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Review Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028804/
https://ncbi.nlm.nih.gov/pubmed/29988669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ams2.343
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