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How is edaravone effective against acute ischemic stroke and amyotrophic lateral sclerosis?

Edaravone is a low-molecular-weight antioxidant drug targeting peroxyl radicals among many types of reactive oxygen species. Because of its amphiphilicity, it scavenges both lipid- and water-soluble peroxyl radicals by donating an electron to the radical. Thus, it inhibits the oxidation of lipids by...

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Detalhes bibliográficos
Publicado no:J Clin Biochem Nutr
Main Authors: Watanabe, Kazutoshi, Tanaka, Masahiko, Yuki, Satoshi, Hirai, Manabu, Yamamoto, Yorihiro
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773834/
https://ncbi.nlm.nih.gov/pubmed/29371752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.17-62
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