Long-term effects of edaravone on survival of patients with amyotrophic lateral sclerosis

BACKGROUND AND PURPOSE: Oxidative stress has been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). Edaravone, a free radical scavenger, was approved as a therapeutic drug for ALS in 2015 in Japan. A phase 3 clinical trial demonstrated a smaller decline in ALS functional scale s...

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Detalhes bibliográficos
Publicado no:eNeurologicalSci
Main Authors: Okada, Masamitsu, Yamashita, Satoshi, Ueyama, Hidetsugu, Ishizaki, Masatoshi, Maeda, Yasushi, Ando, Yukio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006910/
https://ncbi.nlm.nih.gov/pubmed/29928711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ensci.2018.05.001
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