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Genotype-phenotype relationship in hereditary amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease. It is characterized by neuronal loss and degeneration of the upper motor neurons (UMNs) and lower motor neurons (LMNs), and is usually fatal due to respiratory failure within 3–5 years of onset. Although approxi...

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Publicado en:Transl Neurodegener
Autores principales: Yamashita, Satoshi, Ando, Yukio
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513711/
https://ncbi.nlm.nih.gov/pubmed/26213621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-015-0036-y
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