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Genotype-phenotype relationship in hereditary amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease. It is characterized by neuronal loss and degeneration of the upper motor neurons (UMNs) and lower motor neurons (LMNs), and is usually fatal due to respiratory failure within 3–5 years of onset. Although approxi...

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Bibliographische Detailangaben
Veröffentlicht in:Transl Neurodegener
Hauptverfasser: Yamashita, Satoshi, Ando, Yukio
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513711/
https://ncbi.nlm.nih.gov/pubmed/26213621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-015-0036-y
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