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Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon

Membrane proteins in bacteria are cotranslationally inserted into the plasma membrane through the SecYEG translocon. Ribosomes exposing the signal-anchor sequence (SAS) of a membrane protein are targeted to the translocon by the signal recognition particle (SRP) pathway. SRP scans translating riboso...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Draycheva, Albena, Lee, Sejeong, Wintermeyer, Wolfgang
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028451/
https://ncbi.nlm.nih.gov/pubmed/29967439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28262-8
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