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Inferring the Probability of the Derived vs. the Ancestral Allelic State at a Polymorphic Site

It is known that the allele ancestral to the variation at a polymorphic site cannot be assigned with certainty, and that the most frequently used method to assign the ancestral state—maximum parsimony—is prone to misinference. Estimates of counts of sites that have a certain number of copies of the...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Keightley, Peter D., Jackson, Benjamin C.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028244/
https://ncbi.nlm.nih.gov/pubmed/29769282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301120
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