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Inferring the Frequency Spectrum of Derived Variants to Quantify Adaptive Molecular Evolution in Protein-Coding Genes of Drosophila melanogaster

Many approaches for inferring adaptive molecular evolution analyze the unfolded site frequency spectrum (SFS), a vector of counts of sites with different numbers of copies of derived alleles in a sample of alleles from a population. Accurate inference of the high-copy-number elements of the SFS is d...

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Bibliographic Details
Published in:Genetics
Main Authors: Keightley, Peter D., Campos, José L., Booker, Tom R., Charlesworth, Brian
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896206/
https://ncbi.nlm.nih.gov/pubmed/27098912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.188102
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