Reduced disc shedding and phagocytosis of photoreceptor outer segment contributes to kava kava extract-induced retinal degeneration in F344/N rats

There was a significant increase in the incidence of retinal degeneration in F344/N rats chronically exposed to Kava kava extract (KKE) in National Toxicology Program (NTP) bioassay. A retrospective evaluation of these rat retinas indicated a similar spatial and morphological alteration as seen in l...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Toxicol Pathol
Hlavní autoři: Yamashita, Haruhiro, Hoenerhoff, Mark J., Shockley, Keith R., Peddada, Shyamal D., Gerrish, Kevin E., Sutton, Deloris, Cummings, Connie A., Wang, Yu, Julie, Foley F., Behl, Mamta, Waidyanatha, Suramya, Sills, Robert C., Pandiri, Arun R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027611/
https://ncbi.nlm.nih.gov/pubmed/29806545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623318778796
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky