Unique microRNA Alterations in Hepatocellular Carcinomas Arising Either Spontaneously or due to Chronic Exposure to Ginkgo biloba Extract (GBE) in B6C3F1/N Mice

Ginkgo biloba extract (GBE) is used in traditional Chinese medicine as an herbal supplement for improving memory. Exposure of B6C3F1/N mice to GBE in a 2-year National Toxicology Program (NTP) bioassay resulted in a dose-dependent increase in hepatocellular carcinomas (HCC). To identify key microRNA...

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Gepubliceerd in:Arch Toxicol
Hoofdauteurs: Yamashita, Haruhiro, Surapureddi, Sailesh, Kovi, Ramesh C., Bhusari, Sachin, Vu Ton, Thai, Li, Jian-Liang, Shockley, Keith R., Peddada, Shyamal D., Gerrish, Kevin E., Rider, Cynthia V., Hoenerhoff, Mark J., Sills, Robert C., Pandiri, Arun R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077180/
https://ncbi.nlm.nih.gov/pubmed/32306082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02749-8
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