Spontaneous Mesotheliomas in F344/N Rats are Characterized by Dysregulation of Cellular Growth and Immune Function Pathways

Aged male Fischer 344/N rats are prone to developing spontaneous peritoneal mesotheliomas, which arise predominantly from the tunica vaginalis of the testes. A definitive cause for the predominance of this neoplasm in F344/N rats is unknown. Investigation of the molecular alterations that occur in s...

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Udgivet i:Toxicol Pathol
Main Authors: Blackshear, Pamela E., Pandiri, Arun R., Ton, Thai-Vu T., Clayton, Natasha P., Shockley, Keith R., Peddada, Shyamal D., Gerrish, Kevin E., Sills, Robert C., Hoenerhoff, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967937/
https://ncbi.nlm.nih.gov/pubmed/23980201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623313501894
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