Reduced disc shedding and phagocytosis of photoreceptor outer segment contributes to kava kava extract-induced retinal degeneration in F344/N rats

There was a significant increase in the incidence of retinal degeneration in F344/N rats chronically exposed to Kava kava extract (KKE) in National Toxicology Program (NTP) bioassay. A retrospective evaluation of these rat retinas indicated a similar spatial and morphological alteration as seen in l...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Toxicol Pathol
मुख्य लेखकों: Yamashita, Haruhiro, Hoenerhoff, Mark J., Shockley, Keith R., Peddada, Shyamal D., Gerrish, Kevin E., Sutton, Deloris, Cummings, Connie A., Wang, Yu, Julie, Foley F., Behl, Mamta, Waidyanatha, Suramya, Sills, Robert C., Pandiri, Arun R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027611/
https://ncbi.nlm.nih.gov/pubmed/29806545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623318778796
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