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Construction of Hyaluronic Tetrasaccharide Clusters Modified Polyamidoamine siRNA Delivery System

The CD44 protein, as a predominant receptor for hyaluronan (HA), is highly expressed on the surface of multiple tumor cells. HA, as a targeting molecule for a CD44-contained delivery system, increases intracellular drug concentration in tumor tissue. However, due to the weak binding ability of hyalu...

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Библиографические подробности
Опубликовано в: :Nanomaterials (Basel)
Главные авторы: Ma, Yingcong, Sha, Meng, Cheng, Shixuan, Yao, Wang, Li, Zhongjun, Qi, Xian-Rong
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027316/
https://ncbi.nlm.nih.gov/pubmed/29899207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano8060433
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