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Efficient siRNA Delivery Using a Polyamidoamine Dendrimer with a Modified Pentaerythritol Core
PURPOSE: Delivery of siRNA into cells remains a critical challenge. Our lab has shown a novel polyamidoamine (PAMAM) dendrimer with modified pentaerythritol derivative core (PD dendrimer) to exhibit high plasmid DNA transfection efficiency and low cytotoxicity. Here, we evaluate PD dendrimer as a si...
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| Publicado no: | Pharm Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4289905/ https://ncbi.nlm.nih.gov/pubmed/22274556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0676-x |
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