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Cell-Penetrating Peptides to Enhance Delivery of Oligonucleotide-Based Therapeutics

The promise of nucleic acid based oligonucleotides as effective genetic therapies has been held back by their low bioavailability and poor cellular uptake to target tissues upon systemic administration. One such strategy to improve upon delivery is the use of short cell-penetrating peptides (CPPs) t...

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Foilsithe in:Biomedicines
Main Authors: McClorey, Graham, Banerjee, Subhashis
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027240/
https://ncbi.nlm.nih.gov/pubmed/29734750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines6020051
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