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Cell-Penetrating Peptides to Enhance Delivery of Oligonucleotide-Based Therapeutics

The promise of nucleic acid based oligonucleotides as effective genetic therapies has been held back by their low bioavailability and poor cellular uptake to target tissues upon systemic administration. One such strategy to improve upon delivery is the use of short cell-penetrating peptides (CPPs) t...

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Vydáno v:Biomedicines
Hlavní autoři: McClorey, Graham, Banerjee, Subhashis
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027240/
https://ncbi.nlm.nih.gov/pubmed/29734750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines6020051
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