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Cell-penetrating Peptides as Versatile Vehicles for Oligonucleotide Delivery
Short regulatory oligonucleotides (ONs) have a great therapeutic potential for the modulation of gene expression due to their high specificity and low toxicity. The major obstacles for in vivo clinical applications of ONs are the poor permeability of plasma membrane to nucleic acids and the sensitiv...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293609/ https://ncbi.nlm.nih.gov/pubmed/22233581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.284 |
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