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Cell-penetrating Peptides as Versatile Vehicles for Oligonucleotide Delivery
Short regulatory oligonucleotides (ONs) have a great therapeutic potential for the modulation of gene expression due to their high specificity and low toxicity. The major obstacles for in vivo clinical applications of ONs are the poor permeability of plasma membrane to nucleic acids and the sensitiv...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293609/ https://ncbi.nlm.nih.gov/pubmed/22233581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.284 |
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