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Cell-Penetrating Peptides to Enhance Delivery of Oligonucleotide-Based Therapeutics

The promise of nucleic acid based oligonucleotides as effective genetic therapies has been held back by their low bioavailability and poor cellular uptake to target tissues upon systemic administration. One such strategy to improve upon delivery is the use of short cell-penetrating peptides (CPPs) t...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: McClorey, Graham, Banerjee, Subhashis
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027240/
https://ncbi.nlm.nih.gov/pubmed/29734750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines6020051
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