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Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity
Oridonin (Ori) is the major active ingredient of the traditional Chinese medicinal herb Rabdosia rubescens and has anti-inflammatory activity, but the target of Ori remains unknown. NLRP3 is a central component of NLRP3 inflammasome and has been involved in a wide variety of chronic inflammation-dri...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026158/ https://ncbi.nlm.nih.gov/pubmed/29959312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04947-6 |
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