Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

The NLRP3 inflammasome has been implicated in the pathogenesis of a wide variety of human diseases. A few compounds have been developed to inhibit NLRP3 inflammasome activation, but compounds directly and specifically targeting NLRP3 are still not available, so it is unclear whether NLRP3 itself can...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Exp Med
Autores principales: Jiang, Hua, He, Hongbin, Chen, Yun, Huang, Wei, Cheng, Jinbo, Ye, Jin, Wang, Aoli, Tao, Jinhui, Wang, Chao, Liu, Qingsong, Jin, Tengchuan, Jiang, Wei, Deng, Xianming, Zhou, Rongbin
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679172/
https://ncbi.nlm.nih.gov/pubmed/29021150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171419
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares