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CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
RAG endonuclease initiates antibody heavy chain variable region exon assembly from V, D, and J segments within a chromosomal V(D)J recombination center (RC) by cleaving between paired gene segments and flanking recombination signal sequences (RSSs). The IGCR1 control region promotes DJ(H) intermedia...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026039/ https://ncbi.nlm.nih.gov/pubmed/29804837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.04.035 |
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