HIV-1 latent reservoir size and diversity are stable following brief treatment interruption

BACKGROUND. The effect of a brief analytical treatment interruption (ATI) on the HIV-1 latent reservoir of individuals who initiate antiretroviral therapy (ART) during chronic infection is unknown. METHODS. We evaluated the impact of transient viremia on the latent reservoir in participants who unde...

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Pubblicato in:J Clin Invest
Autori principali: Salantes, D. Brenda, Zheng, Yu, Mampe, Felicity, Srivastava, Tuhina, Beg, Subul, Lai, Jun, Li, Jonathan Z., Tressler, Randall L., Koup, Richard A., Hoxie, James, Abdel-Mohsen, Mohamed, Sherrill-Mix, Scott, McCormick, Kevin, Overton, E. Turner, Bushman, Frederic D., Learn, Gerald H., Siliciano, Robert F., Siliciano, Janet M., Tebas, Pablo, Bar, Katharine J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
Soggetti:
Clinical Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026010/
https://ncbi.nlm.nih.gov/pubmed/29911997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120194
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