Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury

Radiographic contrast agents cause acute kidney injury (AKI), yet the underlying pathogenesis is poorly understood. Nod-like receptor pyrin containing 3–deficient (Nlrp3-deficient) mice displayed reduced epithelial cell injury and inflammation in the kidney in a model of contrast-induced AKI (CI-AKI...

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Vydáno v:J Clin Invest
Hlavní autoři: Lau, Arthur, Chung, Hyunjae, Komada, Takanori, Platnich, Jaye M., Sandall, Christina F., Choudhury, Saurav Roy, Chun, Justin, Naumenko, Victor, Surewaard, Bas G.J., Nelson, Michelle C., Ulke-Lemée, Annegret, Beck, Paul L., Benediktsson, Hallgrimur, Jevnikar, Anthony M., Snelgrove, Sarah L., Hickey, Michael J., Senger, Donna L., James, Matthew T., Macdonald, Justin A., Kubes, Paul, Jenne, Craig N., Muruve, Daniel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026009/
https://ncbi.nlm.nih.gov/pubmed/29863495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96640
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