Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure

Progression of chronic kidney disease associated with progressive fibrosis and impaired tubular epithelial regeneration is still an unmet biomedical challenge because, once chronic lesions have manifested, no effective therapies are available as of yet for clinical use. Prompted by various studies a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Tampe, Björn, Tampe, Désirée, Nyamsuren, Gunsmaa, Klöpper, Friederike, Rapp, Gregor, Kauffels, Anne, Lorf, Thomas, Zeisberg, Elisabeth M., Müller, Gerhard A., Kalluri, Raghu, Hakroush, Samy, Zeisberg, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025987/
https://ncbi.nlm.nih.gov/pubmed/29664738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89632
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