Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure

Progression of chronic kidney disease associated with progressive fibrosis and impaired tubular epithelial regeneration is still an unmet biomedical challenge because, once chronic lesions have manifested, no effective therapies are available as of yet for clinical use. Prompted by various studies a...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Tampe, Björn, Tampe, Désirée, Nyamsuren, Gunsmaa, Klöpper, Friederike, Rapp, Gregor, Kauffels, Anne, Lorf, Thomas, Zeisberg, Elisabeth M., Müller, Gerhard A., Kalluri, Raghu, Hakroush, Samy, Zeisberg, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025987/
https://ncbi.nlm.nih.gov/pubmed/29664738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89632
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