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Abundance of clinical variants in exons included in multiple transcripts

Previous studies showed that the magnitude of selection pressure in constitutive exons is higher than that in alternatively spliced exons. The intensity of selection was also shown to be depended on the inclusion level of exons: the number of transcripts that include an exon. Here, we examined how t...

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Detalles Bibliográficos
Publicado en:Hum Genomics
Autor Principal: Subramanian, Sankar
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025840/
https://ncbi.nlm.nih.gov/pubmed/29954439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-018-0166-2
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