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Abundance of clinical variants in exons included in multiple transcripts

Previous studies showed that the magnitude of selection pressure in constitutive exons is higher than that in alternatively spliced exons. The intensity of selection was also shown to be depended on the inclusion level of exons: the number of transcripts that include an exon. Here, we examined how t...

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Publicat a:Hum Genomics
Autor principal: Subramanian, Sankar
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025840/
https://ncbi.nlm.nih.gov/pubmed/29954439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-018-0166-2
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