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Neutral Substitutions Occur at a Faster Rate in Exons Than in Noncoding DNA in Primate Genomes

Point mutation rates in exons (synonymous sites) and noncoding (introns and intergenic) regions are generally assumed to be the same. However, comparative sequence analyses of synonymous substitutions in exons (81 genes) and that of long intergenic fragments (141.3 kbp) of human and chimpanzee genom...

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Bibliografische gegevens
Hoofdauteurs: Subramanian, Sankar, Kumar, Sudhir
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC430942/
https://ncbi.nlm.nih.gov/pubmed/12727904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1152803
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