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Gene Expression Intensity Shapes Evolutionary Rates of the Proteins Encoded by the Vertebrate Genome

Natural selection leaves its footprints on protein-coding sequences by modulating their silent and replacement evolutionary rates. In highly expressed genes in invertebrates, these footprints are seen in the higher codon usage bias and lower synonymous divergence. In mammals, the highly expressed ge...

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Detalhes bibliográficos
Main Authors: Subramanian, Sankar, Kumar, Sudhir
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448110/
https://ncbi.nlm.nih.gov/pubmed/15454550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.028944
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