Sugar additives for MALDI matrices improve signal allowing the smallest nucleotide change (A:T) in a DNA sequence to be resolved

Sample preparation for matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) of DNA is critical for obtaining high quality mass spectra. Sample impurity, solvent content, substrate surface and environmental conditions (temperature and humidity) all affect the rate of matrix–anal...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Shahgholi, Mona, Garcia, Benjamin A., Chiu, Norman H. L., Heaney, Paul J., Tang, Kai
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2001
Matèries:	NAR Methods Online
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11574693/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.19.e91
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