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Unconventional Secretion and Intercellular Transfer of Mutant Huntingtin
The mechanism of intercellular transmission of pathological agents in neurodegenerative diseases has received much recent attention. Huntington’s disease (HD) is caused by a monogenic mutation in the gene encoding Huntingtin (HTT). Mutant HTT (mHTT) harbors a CAG repeat extension which encodes an ab...
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| 發表在: | Cells |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6025013/ https://ncbi.nlm.nih.gov/pubmed/29904030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7060059 |
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