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Unconventional Secretion and Intercellular Transfer of Mutant Huntingtin

The mechanism of intercellular transmission of pathological agents in neurodegenerative diseases has received much recent attention. Huntington’s disease (HD) is caused by a monogenic mutation in the gene encoding Huntingtin (HTT). Mutant HTT (mHTT) harbors a CAG repeat extension which encodes an ab...

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Detalhes bibliográficos
Publicado no:Cells
Autor principal: Tang, Bor Luen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025013/
https://ncbi.nlm.nih.gov/pubmed/29904030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7060059
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