Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNK signaling

UVB exposure can contribute to the development of skin cancer by modulating protein tyrosine kinase (PTK) signaling. It has been suggested that UVB radiation increases the ligand-dependent activation of PTKs and induces PTP inactivation. Our recent studies have shown that T-cell protein tyrosine pho...

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Udgivet i:Cell Death Dis
Main Authors: Baek, Minwoo, Kim, Mihwa, Lim, Jae Sung, Morales, Liza D., Hernandez, Joselin, Mummidi, Srinivas, Williams-Blangero, Sarah, Jang, Ik-Soon, Tsin, Andrew T., Kim, Dae Joon
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023867/
https://ncbi.nlm.nih.gov/pubmed/29955047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0781-9
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