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Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics
OBJECTIVE—: Platelet activation after stimulation of PAR (protease-activated receptor) 4 is heightened in platelets from blacks compared with those from whites. The difference in PAR4 signaling by race is partially explained by a single-nucleotide variant in PAR4 encoding for either an alanine or th...
שמור ב:
| הוצא לאור ב: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Lippincott Williams & Wilkins
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6023764/ https://ncbi.nlm.nih.gov/pubmed/29748334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311112 |
| תגים: |
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