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Germinal Center Responses to Complex Antigens
Germinal centers (GCs) are the primary sites of antibody affinity maturation, sites where B-cell antigen-receptor (BCR) genes rapidly acquire mutations and are selected for increasing affinity for antigen. This process of hypermutation and affinity-driven selection results in the clonal expansion of...
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| 出版年: | Immunol Rev |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6023402/ https://ncbi.nlm.nih.gov/pubmed/29944756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12661 |
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