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Complex Antigens Elicit Diverse Patterns of Clonal Selection in Germinal Centers
Germinal center (GC) B cells evolve towards increased affinity by a Darwinian process that has been studied primarily in genetically restricted, hapten-specific responses. We explored the population dynamics of genetically diverse GC responses to two complex antigens – Bacillus anthracis protective...
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| Publicado no: | Immunity |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794380/ https://ncbi.nlm.nih.gov/pubmed/26948373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.02.010 |
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