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High content, high-throughput screening for small molecule inducers of NF-κB translocation
NF-κB is an important mediator of immune activity and its activation is essential in mounting immune response to pathogens. Here, we describe the optimization and implementation of a high-throughput screening platform that utilizes high content imaging and analysis to monitor NF-κB nuclear transloca...
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| Pubblicato in: | PLoS One |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6023200/ https://ncbi.nlm.nih.gov/pubmed/29953522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199966 |
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